Skip to main content

A Simulated C. Elegans Connectome Demonstrates Live Organism Behaviors

Using the well-mapped connectome of the nematode Caenorhabditis Elegans (C. Elegans), it is possible to create programs that represent each of the worm’s 302 neurons and use interprocess communications to connect the programs together in a manner similar to that of synaptic communication.

Wrapping the entire connectome into a framework where sensory input can be derived from robotic sensors and directed to sensory neurons allows, in turn, activation of interneurons and motor neurons, and ultimately accumulation of muscle output to activate robotic motors. The connectome and connectome framework allows for a biological simulation and study of the entire connectome from sensory input to muscular output.

These experiments demonstrate that the connectome alone is enough to give rise to experimental behaviors shown in the biological organism. This, in part, answers the age old question of whether the connectome alone can have value in determining animal phenotypes.

Timothy has a minor background in the Neurosciences and a degree in Computer Science.